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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
18.18
Human Site:
S15
Identified Species:
30.77
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
S15
M
Y
R
N
P
G
P
S
G
P
Q
L
R
D
F
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
S15
M
Y
R
N
P
G
P
S
G
P
Q
L
R
D
F
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
S15
M
Y
R
N
L
G
P
S
G
P
Q
L
R
D
F
Dog
Lupus familis
XP_535342
274
31382
S15
M
Y
R
N
P
G
S
S
G
P
Q
L
R
D
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
S15
M
Y
R
N
P
G
P
S
G
P
Q
P
R
D
F
Rat
Rattus norvegicus
O70257
261
29832
A15
G
G
D
P
A
Q
L
A
Q
R
I
S
S
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
C8
M
Y
S
V
S
S
G
C
I
Q
G
L
S
Q
A
Chicken
Gallus gallus
XP_001232002
272
30779
A15
P
Y
R
P
G
P
T
A
P
P
R
D
F
G
G
Frog
Xenopus laevis
NP_001079671
259
29246
S17
S
Q
L
A
Q
I
I
S
G
N
I
Q
K
I
T
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
P15
S
S
H
S
Q
S
Q
P
R
D
F
N
N
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
H29
V
A
V
N
V
D
G
H
D
S
Y
M
D
D
F
Honey Bee
Apis mellifera
XP_396269
271
30684
R15
Y
H
N
G
G
P
T
R
E
Q
D
F
G
R
L
Nematode Worm
Caenorhab. elegans
O16000
291
33234
N28
D
M
H
M
D
T
G
N
A
Q
Y
M
E
E
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
R22
P
N
R
F
T
G
G
R
Q
Q
R
P
S
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
0
N.A.
20
20
13.3
0
N.A.
20
0
6.6
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
20
33.3
20
6.6
N.A.
33.3
6.6
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
0
0
15
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
0
0
8
8
8
8
8
43
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
8
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
8
8
0
50
% F
% Gly:
8
8
0
8
15
43
29
0
43
0
8
0
8
8
8
% G
% His:
0
8
15
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
0
8
0
15
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
8
0
8
0
8
0
0
0
0
36
0
8
8
% L
% Met:
43
8
0
8
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
0
8
8
43
0
0
0
8
0
8
0
8
8
8
0
% N
% Pro:
15
0
0
15
29
15
29
8
8
43
0
15
0
0
0
% P
% Gln:
0
8
0
0
15
8
8
0
15
29
36
8
0
8
0
% Q
% Arg:
0
0
50
0
0
0
0
15
8
8
15
0
36
8
8
% R
% Ser:
15
8
8
8
8
15
8
43
0
8
0
8
22
8
0
% S
% Thr:
0
0
0
0
8
8
15
0
0
0
0
0
0
0
15
% T
% Val:
8
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
50
0
0
0
0
0
0
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _